The Transcription of the Reovirus Genome
This extract was created in the absence of an abstract.
Excerpt
Reoviruses have been isolated from a variety of mammals and birds including monkeys, cattle, dogs, mice, and chickens. In spite of their widespread distribution and their recovery from children ill with diarrhea and mild respiratory disease, the
[Graphics Excised]. Electron micrographs of reovirions (A), and reovirion cores (B). Both types of particles were isolated from the bands of CsCl equilibrium density gradients. Both preparations were stained with 1% phosphotungstic acid pH 7 and examined in a A.E.I.-EM6B electron microscope. The magnification is the same for both. Note that the structural arrangement of the outer and inner shells of reovirions differs greatly. The outer shell is clearly an array of relatively few large capsomeres; the inner shell consists of far smaller subunits. Cores exhibit regularly spaced projections, the polypeptide constitution of which is not known. (From Smith et al., 1969.)...
importance of reoviruses (Respiratory Enteric Orphan) in human disease has not
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↵* Present Address: National Institute for Medical Research, Mill Hill, London.
